Methods for producing polypeptide binding sites, monoclonal antibodies and compositions thereof
US6955900B1 · kind B1 · utility
23Cited by
4References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 2, 1994 |
| Grant date | Oct 18, 2005 |
| Priority date | — |
| Expiry date | Feb 2, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2318/10
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention describes methods for producing binding sites on polypeptides, and particularly for producing binding sites within the CDR regions of immunoglobulin heavy or light chains that are displayed on the surface of filamentous phage particles. The invention also describes oligonucleotides useful for preparing the binding sites, and human monoclonal antibodies produced by the present methods.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.