Crystalline antifungal polymorph
US6958337B2 · kind B2 · utility
8Cited by
1References
7Claims
0Family size
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Key dates
| Filing date | Feb 25, 2004 |
| Grant date | Oct 25, 2005 |
| Priority date | — |
| Expiry date | Feb 25, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D233/56
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The crystalline polymorph Form I of (−)-4-[4-[4-[4-[[(2R-cis)-5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methoxy]phenyl]-1-piperazinyl]phenyl-2,4-dihydro-2-[(S)-1-ethyl-2(S)-hydroxylpropyl]-3H-1,2,4-triazol-3-one represented by the formula I pharmaceutical compositions containing such a polymorph and methods of using such a polymorph to treat fungal infections in mammals are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.