Separate-cistron contructs for secretion of aglycosylated antibodies from prokaryotes
US6979556B2 · kind B2 · utility
56Cited by
15References
27Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 13, 2001 |
| Grant date | Dec 27, 2005 |
| Priority date | — |
| Expiry date | May 19, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides methods and compositions for improved expression and production of recombinant antibodies in prokaryotic expression systems. Particularly contemplated are prokaryotic expression and production of full length aglycosylated antibodies. The antibody products of the invention can be used in various aspects of biological research, diagnosis and medical treatment.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.