Method of complexing a nucleic acid with a lipid-conjugated polyamide
US6982092B2 · kind B2 · utility
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4Claims
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Key dates
| Filing date | May 30, 2003 |
| Grant date | Jan 3, 2006 |
| Priority date | — |
| Expiry date | Dec 11, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/645
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
In accordance with the present invention, there are provided lipid-conjugated polyamide compounds and related compositions and methods thereof. Lipid-conjugated polyamide compounds of the present invention are particularly useful as vehicles for delivering biologically active agents to a target site. In particular, the invention compounds are effective at facilitating the delivery of polynucleotides to cells. The present invention also provides a method for producing stable formulations of polynucleotides complexed with a delivery vehicle.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.