Cyclic β-amino acid derivatives as inhibitors of matrix metalloproteases and TNF-α
US6984648B2 · kind B2 · utility
10Cited by
1References
21Claims
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Key dates
| Filing date | Feb 13, 2004 |
| Grant date | Jan 10, 2006 |
| Priority date | — |
| Expiry date | Feb 13, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present application describes novel cyclic β-amino acid derivatives of formula I: or pharmaceutically acceptable salt forms thereof, wherein ring B is a 5-7 membered cyclic system containing from 0-2 heteroatoms selected from O, N, NRa, and S(O)p, and 0-1 carbonyl groups and the other variables are defined in the present specification, which are useful as metalloprotease and/or as TNF-α inhibitors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.