Patent · US Expired

Immunogenic Hepatitis C virus non-structural polypeptides

US6986892B1 · kind B1 · utility

18Cited by
5References
19Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 22, 2000
Grant dateJan 17, 2006
Priority date
Expiry dateNov 22, 2020

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2770/24222
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Polypeptides comprising a mutant non-structural Hepatitis C virus useful in diagnostic and/or immunogenic compositions are disclosed, in which the mutant is an N-terminal mutation that functionally disrupt the catalytic domain of NS3. Polynucleotides encoding these polypeptides, host cells transformed with polynucleotides and methods of using the polypeptides and polynucleotides are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.