Patent · US Expired

Compositions and methods for treatment of hepatitis C virus-associated diseases

US6995146B2 · kind B2 · utility

24Cited by
12References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 11, 2001
Grant dateFeb 7, 2006
Priority date
Expiry dateNov 17, 2022

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2770/24222
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Antisense oligonucleotides are provided which are complementary to and hybridizable with at least a portion of HCV RNA and which are capable of inhibiting the function of the HCV RNA. These oligonucleotides can be administered to inhibit the activity of Hepatitis C virus in vivo or in vitro. These compounds can be used either prophylactically or therapeutically to reduce the severity of diseases associated with Hepatitis C virus, and for diagnosis and detection of HCV and HCV-associated diseases. Methods of using these compounds are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.