Cloning and expression of a novel 5-HT4 receptor

US6998244B1 · kind B1 · utility

Assignee

• Janssen Pharmaceutica NA · BE

Inventors

• Eckhard Bender · Langenfeld, DE
• Armelle Nathalie Françoise Pindon · Ekeren, BE
• Irma Petronella Van Oers · Zundert, NL
• Mirek Jurzak · Breda, NL
• Walter Luyten · Beerse, BE

Key dates

• Filing date: Jun 14, 2000
• Grant date: Feb 14, 2006
• Expiry date: Sep 5, 2021

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

There is disclosed an isolated or substantially pure form of a nucleic acid molecule encoding a human 5-HT4(h) receptor, which 5-HT4(h) receptor preferably comprises the sequence illustrated in FIG. 1B. Also provided by the invention are expression vectors incorporating said nucleic acid molecule in addition to transgenic cells, tissues or organisms transfected with the nucleic acid molecule.