Quinoline derivatives

US7012073B2 · kind B2 · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Michael G. Klug · Brooklyn Park, US
• Patrizio Mattei · Riehen, CH
• Werner Mueller · Cologne, DE
• Werner Neidhart · Hagenthal-le-Bas, FR
• Matthias Nettekoven · Weil am Rhein, DE
• Philippe Pflieger · Schwoben, FR
• Jean-Marc Plancher · Rixheim, FR

Key dates

• Filing date: Jul 22, 2004
• Grant date: Mar 14, 2006
• Expiry date: Jul 22, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D405/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of formula I as well as pharmaceutically acceptable salts and esters thereof, wherein R1, R2, R3, A1 and A2 have the significance given in claim 1, can be used in the form of pharmaceutical preparations for the treatment or prevention of arthritis, cardiovascular diseases, diabetes, renal failure, eating disorders and obesity.