Antibodies to the protein product encoded by ORF3 of the TRP-1 gene and compositions and kits thereof
US7015312B1 · kind B1 · utility
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15Claims
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Key dates
| Filing date | May 16, 2000 |
| Grant date | Mar 21, 2006 |
| Priority date | — |
| Expiry date | May 16, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2239/57
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention discloses that the normal melanogenic gene, gp75 gene, encodes a gene product, a 24 amino acid peptide of ORF3, which is processed to an antigenic cancer peptide recognized by T lymphocytes. The cancer peptide of the invention derived from ORF3 is recognized by cancer antigen specific T lymphocytes as a tumor rejection antigen. The products of this gene are promising candidates for immunotherapeutic strategies for the treatment and diagnosis of patients with cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.