Delivery system for nucleic acids

US7025987B2 · kind B2 · utility

Assignees

• THE SCRIPPS RESEARCH INSTITUTE · US
• Board of Trustees Leland Stanford Jr University · US

Inventors

• David A. Cheresh · Village of La Jolla, US
• John Hood · San Diego, US
• Mark D. Bednarski · Flint, US

Key dates

• Filing date: May 30, 2002
• Grant date: Apr 11, 2006
• Expiry date: Jun 22, 2023

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K48/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

αvβ3 Integrin receptor targeting liposomes comprise a cationic amphiphile such as a cationic lipid, a neutral lipid, and a targeting lipid. The targeting lipid includes a non-peptidic αvβ3 integrin antagonist.