Stabilized liquid polypeptide-containing pharmaceutical compositions
US7030086B2 · kind B2 · utility
8Cited by
11References
46Claims
0Family size
Assignee
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Key dates
| Filing date | Nov 18, 2002 |
| Grant date | Apr 18, 2006 |
| Priority date | — |
| Expiry date | Dec 17, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Stabilized liquid polypeptide-containing pharmaceutical compositions are provided. The compositions comprise an amino acid base, which serves as the primary stabilizing agent of the polypeptide, and an acid and/or its salt form to buffer the solution within an acceptable pH range for stability of the polypeptide. The compositions are near isotonic. Methods for increasing stability of a polypeptide in a liquid pharmaceutical composition and for increasing storage stability of such a pharmaceutical composition are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.