Heteroaryl substituted spriocyclic sulfamides for inhibition of gamma secretase
US7041689B2 · kind B2 · utility
3Cited by
3References
16Claims
0Family size
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Inventors
Key dates
| Filing date | Apr 24, 2003 |
| Grant date | May 9, 2006 |
| Priority date | — |
| Expiry date | Apr 24, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of formula I are disclosed: in which X is a 5-membered heteroaryl ring and R is as defined herein. The compounds are inhibitors of the processing of APP by gamma-secretase, and hence are useful in the treatment or prevention of Alzheimer's disease
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.