Redirection of cellular immunity by receptor chimeras
US7049136B2 · kind B2 · utility
120Cited by
10References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 2, 1999 |
| Grant date | May 23, 2006 |
| Priority date | — |
| Expiry date | Apr 22, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2799/023
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed is a method of directing a cellular response in a mammal by expressing in a cell of the mammal a chimeric receptor which causes the cells to specifically recognize and destroy an infective agent, a cell infected with an infective agent, a tumor or cancerous cell, or an autoimmune-generated cell. Also disclosed are cells which express the chimeric receptors and DNA encoding the chimeric receptors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.