Camptothecin analogs having an E-ring ketone
US7071204B2 · kind B2 · utility
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23References
16Claims
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Key dates
| Filing date | Jun 30, 2003 |
| Grant date | Jul 4, 2006 |
| Priority date | — |
| Expiry date | Aug 29, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Camptothecin analogs having an E-ring ketone are effective anti tumor compounds. These compounds inhibit the enzyme topoisomerase I and may alkylate DNA of the associated topoisomerase I DNA cleavable complex.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.