Humanization of murine antibody
US7087409B2 · kind B2 · utility
283Cited by
2References
12Claims
0Family size
Assignee
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Key dates
| Filing date | Feb 19, 2002 |
| Grant date | Aug 8, 2006 |
| Priority date | — |
| Expiry date | Dec 17, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A humanized murine antibody is provided. The amino acid sequences of a light chain complementarity determining region from a mouse antibody are grafted onto a human light chain, and a heavy chain complementarity determining region from a mouse antibody are grafted onto a human antibody heavy chain to produce libraries from which a humanized murine antibody having the desired specificity is selected.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.