5,8-Dihydro-6H-pyrido[2,3-d]pyrimidin-7-ones
US7098332B2 · kind B2 · utility
13Cited by
1References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 8, 2003 |
| Grant date | Aug 29, 2006 |
| Priority date | — |
| Expiry date | Aug 9, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides 5,8-dihydro-6H-pyrido[2,3-d]pyrimidin-7-one compounds that are selective inhibitors of KDR and FGFR kinases, and are useful in the treatment of cancers. The compounds have the generic structure Iwhere Ar, Ar′, and R1 are as set forth in the present specification. The invention also provides pharmaceutical compositions containing these compounds and methods for their use.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.