Nitric oxide-releasing imidate and thioimidate diazeniumdiolates

US7105502B2 · kind B2 · utility

Assignee

• The United States of America, as represented by the Department of Health and Human Services · US

Inventors

• Ernst Arnold · Hagerstown, US
• Larry K. Keefer · Bethesda, US
• Joseph A. Hrabie · Frederick, US

Key dates

• Filing date: Nov 6, 2003
• Grant date: Sep 12, 2006
• Expiry date: Jul 21, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C257/06
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention provides NO- or NO−-releasing imidate; and thioimidate, diazeniumdiolates, in which the N2O2− functional group is bonded to a carbon atom. The imidate and thioimidate diazeniumdiolates are bound to a polymer or a substrate.