Method for producing yeast expressed HPV types 6 and 16 capsid proteins
US7112330B1 · kind B1 · utility
9Cited by
1References
17Claims
0Family size
Assignee
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Key dates
| Filing date | Aug 13, 1999 |
| Grant date | Sep 26, 2006 |
| Priority date | — |
| Expiry date | Aug 13, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/108
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Mosaic VLPs of viral capsid proteins from different virus types are described, as are methods of making the same. Specifically, a diploid yeast strain that coexpresses the L1 and L2 capsid proteins of both HPV-6 and HPV-16 as mosaic VLPs is described. The mosaic VLPs induced the production conformational antibodies against both L1 proteins upon administration to mice.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.