Substituted 2-carba-3,5-dicyano-4-aryl-6-aminopyridines and the use of the same as selective ligands of the adenosine receptor

US7129255B2 · kind B2 · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Ulrich Rosentreter · Binnen, DE
• Thomas Kramer · Wuppertal, DE
• Andrea Vaupel · Riehen, CH
• Walter Hubsch · Wuppertal, DE
• Nicole Diedrichs · Wuppertal, DE
• Thomas Krahn · Hagen, DE
• Klaus Dembowsky · Boston, US
• Johannes-Peter Stasch · Wuppertal, DE
• Mitsuyuki Shimada · Nara, JP

Key dates

• Filing date: Mar 25, 2002
• Grant date: Oct 31, 2006
• Expiry date: Dec 11, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D213/85
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This application relates to compounds of the formulawherein the groups R1–R6 are as defined in the specification and claims, and to a pharmaceutical composition containing the same, and to a method of using the same in treatment of cardiovascular disorders.