Antidepressant arylpiperazine derivatives of hetrocycle-fused benzodioxans

US7153849B2 · kind B2 · utility

Assignee

• Wyeth, LLC · US

Inventors

• Deborah Evrard · Hamilton Square, US
• Dahui Zhou · Groton, US
• Gary P. Stack · Ambler, US
• Aranapakam Venkatesan · Chadds Ford, US
• Amedeo A. Failli · Princeton Junction, US
• Susan Croce · Lambertville, US

Key dates

• Filing date: Sep 10, 2003
• Grant date: Dec 26, 2006
• Expiry date: Sep 10, 2023

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02P20/582
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of the formula I:are useful for the treatment of depression (including but not limited to major depressive disorder, childhood depression and dysthymia), anxiety, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder (also known as pre-menstrual syndrome), attention deficit disorder (with and without hyperactivity), obsessive-compulsive disorder, social anxiety disorder, generalized anxiety disorder, obesity, eating disorders such as anorexia nervosa and bulimia nervosa, vasomotor flushing, cocaine and alcohol addiction, sexual dysfunction and related illnesses.