Cannabimimetic lipid amides as useful medications
US7161016B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 24, 1999 |
| Grant date | Jan 9, 2007 |
| Priority date | — |
| Expiry date | Nov 24, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C247/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel analogs of arachidonylethanolamide are presented which have higher affinities for the cannabinoid CB1 and/or CB2 receptor sites. Further, most of the analogs exhibit greater metabolic stability than arachidonylethanolamide. The improved receptor affinity and selectivity and/or greater metabolic stability make these analogs therapeutically useful as medications for relief of pain caused by cancer and nausea caused by chemotherapy, as well as for peripheral pain. The compounds may also be useful as oral and topical contraceptives, in suppression of the immune system, enhancement of appetite and in treatment of psychomotor disorders, multiple sclerosis and hypertension.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.