Quinoline derivatives

US7166589B2 · kind B2 · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Michael G. Klug · Brooklyn Park, US
• Patrizio Mattei · Riehen, CH
• Werner Mueller · Cologne, DE
• Werner Neidhart · Hagenthal-le-Bas, FR
• Matthias Nettekoven · Weil am Rhein, DE
• Philippe Pflieger · Schwoben, FR
• Jean-Marc Plancher · Rixheim, FR

Key dates

• Filing date: Mar 16, 2006
• Grant date: Jan 23, 2007
• Expiry date: Mar 16, 2026

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D405/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of formula Ias well as pharmaceutically acceptable salts and esters thereof, wherein R1, R2, R3, A1 and A2 have the significance given in claim 1, can be used in the form of pharmaceutical preparations for the treatment or prevention of arthritis, cardiovascular diseases, diabetes, renal failure, eating disorders and obesity.