Trisubstituted pyrimidines

US7166599B2 · kind B2 · utility

Assignee

• BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG · DE

Inventors

• Klaus Bornemann · Ingelheim am Rhein, DE
• Hans Briem · Bremen, DE
• Cornelia Dorner-Ciossek · Ingelheim am Rhein, DE
• Katja Fechteler · Wiesbaden, DE
• Klaus Fuchs · Ingelheim am Rhein, DE
• Frank Himmelsbach · Mittelbiberach, DE
• Klaus Klinder · Oggelshausen, DE
• Markus Kostka · Mainz, DE

Key dates

• Filing date: Dec 9, 2004
• Grant date: Jan 23, 2007
• Expiry date: Dec 9, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D403/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to trisubstituted pyrimidines of formulawhereinRa to Re are defined as in claim 1, which are suitable for the treatment of illnesses in which β-amyloid modulators have a therapeutic benefit, the use thereof for preparing a pharmaceutical composition with the abovementioned properties, and processes for the preparation thereof.