Tetrahydropyranyl cyclopentyl tetrahydroisoquinoline modulators of chemokine receptor activity
US7166614B2 · kind B2 · utility
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27Claims
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Key dates
| Filing date | Apr 25, 2003 |
| Grant date | Jan 23, 2007 |
| Priority date | — |
| Expiry date | Apr 25, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/052
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to compounds of the formula I: I(wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n and the dashed line are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.