Composite antibodies of humanized human subgroup IV light chain capable of binding to TAG-72

US7179899B2 · kind B2 · utility

Assignee

• The United States of America, as represented by the Department of Health and Human Services · US

Inventors

• Peter Mezes · Old Lyme, US
• Ruth A. Richard · Midland, US
• Kimberly Johnson · New York, US
• Jeffrey Schlom · Potomac, US
• Syed V. S. Kashmiri · North Potomac, US
• Liming Shu · Gaithersburg, US
• Eduardo A. Padlan · Kensington, US

Key dates

• Filing date: Sep 25, 2002
• Grant date: Feb 20, 2007
• Expiry date: Jul 30, 2023

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S530/867
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Novel composite and humanized anti-TAG-72 monoclonal antibodies, antibody fragments, and derivatives thereof using human subgroup IV kappa light chain framework regions.