Polymorphs of a 1-pyrrole derivative, intermediate for the preparation of atorvastatin
US7186848B2 · kind B2 · utility
1Cited by
2References
7Claims
0Family size
Assignee
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Key dates
| Filing date | Sep 13, 2002 |
| Grant date | Mar 6, 2007 |
| Priority date | — |
| Expiry date | Oct 7, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to new crystalline forms I and II of (4R-cis)-6-[2-[3-phenyl-4-(phenyl-carbamoyl)-2-(4-fluoro-phenyl)-5-(1- methyl-ethyl)-pyrrol-1-yl]-ethyl]-2,2-dimethyl-[1,3]dioxane-4-yl-acetic acid-tertiary butyl ester of the Formula (I) and a process for the preparation thereof. The new polymorphs of the present invention are useful pharmaceutical intermediates which can be used in the preparation of the hydroxymethyl-glutaryl coenzyme (HMG-COA) reducing enzyme inhibitor having the INN (International Non-proprietory Name) atorvastatin
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.