Substituted bicyclic pyrimidinones as a mitotic kinesin KSP inhibitors
US7192949B2 · kind B2 · utility
19Cited by
1References
9Claims
0Family size
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Inventors
Key dates
| Filing date | Apr 24, 2006 |
| Grant date | Mar 20, 2007 |
| Priority date | — |
| Expiry date | Apr 24, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D403/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to cycloalkylpyrimidinone compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.