Mammalian cells that have increased proliferative capacity

US7195911B2 · kind B2 · utility

Assignees

• Geron Corporation · US
• The Regents of the University of Colorado · US

Inventors

• Thomas R. Cech · Frederick, US
• Joachim Lingner · Épalinges, CH
• Toru Nakamura · Boulder, US
• Karen B. Chapman · Sausalito, US
• Gregg B. Morin · Davis, US
• Calvin B. Harley · Palo Alto, US
• William H. Andrews · Reno, US

Key dates

• Filing date: Jan 11, 2002
• Grant date: Mar 27, 2007
• Expiry date: Apr 20, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q2600/158
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention is directed to cells comprising a recombinant polynucleotide sequence that encodes a telomerase reverse transcriptase protein, variant, or fragment having telomerase catalytic activity when complexed with a telomerase RNA.