Thomas R. Cech
42Patents
19h-index
13Co-inventors
78Inventor score
Filing activity: Dec 3, 1986 → Aug 21, 2009
Most-cited inventions
| Patent | Title | Area | Cited by | Status |
|---|---|---|---|---|
| US4987071A | RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods | Chemistry; Metallurgy | 483 | Expired |
| US5093246A | RNA ribozyme polymerases, dephosphorylases, restriction endoribo-nucleases and methods | Chemistry; Metallurgy | 215 | Expired |
| US5116742A | RNA ribozyme restriction endoribonucleases and methods | Chemistry; Metallurgy | 157 | Expired |
| US5180818A | Site specific cleavage of single-stranded DNA | Chemistry; Metallurgy | 87 | Expired |
| US6261836A | Telomerase | Chemistry; Metallurgy | 76 | Expired |
| US6475789B1 | Human telomerase catalytic subunit: diagnostic and therapeutic methods | Chemistry; Metallurgy | 62 | Expired |
| US6166178A | Telomerase catalytic subunit | Emerging Cross-Sectional Technologies | 60 | Expired |
| US6444650B1 | Antisense compositions for detecting and inhibiting telomerase reverse transcriptase | Chemistry; Metallurgy | 54 | Expired |
| US6093809A | Telomerase | Chemistry; Metallurgy | 53 | Expired |
| US6617110B1 | Cells immortalized with telomerase reverse transcriptase for use in drug screening | Emerging Cross-Sectional Technologies | 48 | Expired |
| US5354855A | RNA Ribozyme which cleaves substrate RNA without formation of a convalent bond | Chemistry; Metallurgy | 46 | Expired |
| US5854038A | Localization of a therapeutic agent in a cell in vitro | Chemistry; Metallurgy | 44 | Expired |
| US6696250B1 | RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods | Chemistry; Metallurgy | 38 | Expired |
| US7262288B1 | Nucleic acids encoding human telomerase reverse transcriptase and related homologs | Chemistry; Metallurgy | 29 | Expired |
| US5037746A | RNA ribozyme polymerases, and methods | Chemistry; Metallurgy | 26 | Expired |
| US6309867A | Telomerase | Chemistry; Metallurgy | 25 | Expired |
| US7195911B2 | Mammalian cells that have increased proliferative capacity | Chemistry; Metallurgy | 23 | Expired |
| US6627619B2 | Antisense compositions for detecting and inhibiting telomerase reverse transcriptase | Chemistry; Metallurgy | 22 | Expired |
| US6927285B2 | Genes for human telomerase reverse transcriptase and telomerase variants | Chemistry; Metallurgy | 19 | Expired |
| US5667969A | Alteration of sequence of a deleterious target molecule by ribozyme catalyzed trans-splicing | Chemistry; Metallurgy | 18 | Expired |
| US6025167A | RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods | Chemistry; Metallurgy | 18 | Expired |
| US7056513B2 | Telomerase | Chemistry; Metallurgy | 16 | Expired |
| US5869254A | Alteration of sequence of a target molecule by ribozyme catalyzed trans-splicing | Chemistry; Metallurgy | 13 | Expired |
| US7297488B2 | Identifying and testing antisense oligonucleotides that inhibit telomerase reverse transcriptase | Chemistry; Metallurgy | 13 | Expired |
| US6808880B2 | Method for detecting polynucleotides encoding telomerase | Chemistry; Metallurgy | 12 | Expired |
Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.