Mass spectrometer and method of analyzing isomers
US7211790B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 19, 2005 |
| Grant date | May 1, 2007 |
| Priority date | — |
| Expiry date | May 19, 2025 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N30/8679
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention intends to determine a presence ratio between mixed compounds which are difficult to separate from each other by a separation unit and cannot be discriminated by MS. In a mass spectrometer with an MSn analysis function for ionizing a sample eluted from a separation unit for separating the sample into individual components, fragmenting an ion of a desired mass number, and performing a mass analysis of fragment ions, the mass spectrometer includes a database storing correlation information between an isomer presence ratio and a particular ion intensity ratio in a mass spectrum per isomer. An isomer ratio can be clarified even for a mixed sample of isomers, such as enantiomers, which are difficult to separate from each other by the separation unit and cannot be discriminated by MS.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.