Modulation of HIF1α and HIF2α expression
US7217572B2 · kind B2 · utility
120Cited by
6References
18Claims
0Family size
Assignee
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Key dates
| Filing date | Nov 21, 2003 |
| Grant date | May 15, 2007 |
| Priority date | — |
| Expiry date | Dec 4, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/346
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds, compositions and methods are provided for modulating the expression of HIF1α and/or HIF2α. The compositions comprise oligonucleotides, targeted to nucleic acid encoding HIF1α and HIF2α. Methods of using these compounds for modulation of HIF1α and/or HIF2α expression and for diagnosis and treatment of disease associated with expression of HIF1α and/or HIF2α are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.