8-fluoroimidazo 1,2-a pyridine derivatives as ligands for GABA receptors
US7226926B2 · kind B2 · utility
3Cited by
3References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 23, 2003 |
| Grant date | Jun 5, 2007 |
| Priority date | — |
| Expiry date | Oct 28, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/28
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A class of 8-fluoroimidazo[1,2-α]pyridine derivatives, substituted at the 3-position by an optionally substituted five-membered or six-membered heteroaromatic ring, being selective ligands for GABAA receptors, in particular having high affinity for the α2 and/or α3 and/or α5 subunit thereof, are accordingly of benefit in the treatment and/or prevention of adverse conditions of the central nervous system, including anxiety, convulsions and cognitive disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.