Patent · US Expired

Use of 2-amino-thiazoline derivatives as inhibitors of inducible no-synthase

US7227022B2 · kind B2 · utility

0Cited by

2References

1Claims

0Family size

Assignee

AVENTIS PHARMA S.A. · FR

Inventors

Antony Bigot · Massy, FR
Jean-Christophe Carry · Saint-Maur-des-Fossés, FR
Serge Mignani · Livry-Gargan, FR

Key dates

Filing date	Aug 10, 2005
Grant date	Jun 5, 2007
Priority date	—
Expiry date	Dec 8, 2025

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D417/14
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to a process for preparing 2-amino-thiazoline derivatives of formula (II):in which either Y is a methylene (CH2) and X is chosen from the following groups: O, NH, (C1–C4) N-Alkyl, N-Bn, N-Ph, N-(2-Py), N-(3-Py), N-(4-Py), N-2-pyrimidyl, N-5-pyrimidyl, S, SO, SO2, CH2 or CHPh; or Y is a carbonyl (C═O) and X is chosen from the following groups: NH, N-Ph, N-(2-Py), N-(3-Py), N-(4-Py), N-2-pyrimidyl or N-5-pyrimidyl.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.