Process for the preparation of the insulin sensitizer

US7259176B2 · kind B2 · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Wolfgang Goehring · Steinen, DE
• Ursula Hoffmann · Muttenz, CH
• Michelangelo Scalone · Birsfelden, CH
• Helmut Stahr · Lörrach, DE
• Shaoning Wang · Basel, CH

Key dates

• Filing date: Jun 21, 2004
• Grant date: Aug 21, 2007
• Expiry date: Oct 28, 2025

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P3/10
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A novel process for the preparation of compounds of formula Iand optionally converting a compound of formula I into a pharmaceutically acceptable salt is disclosed. The compounds of formula I and the corresponding salts, e.g. the sodium salts, are pharmaceutically active substances. Processes for the creation of intermediates are also disclosed.