Inhibitors of serine proteases, particularly HCV NS3-NS4A protease
US7273885B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 11, 2003 |
| Grant date | Sep 25, 2007 |
| Priority date | — |
| Expiry date | Nov 29, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/1027
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to compounds that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The invention further relates to compositions comprising these compounds either for ex vivo use or for administration to a patient suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a patient by administering a composition comprising a compound of this invention. The invention further relates to processes for preparing these compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.