Methods of the treatment or prevention of exercise-induced asthma using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione

US7276529B2 · kind B2 · utility

Assignee

• CELGENE CORPORATION · US

Inventors

• George W. Muller · Northbrook, US
• Peter Schafer · Ottersheim, DE
• Patricia Rohane · Florham Park, US

Key dates

• Filing date: Mar 28, 2006
• Grant date: Oct 2, 2007
• Expiry date: Mar 28, 2026

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07B2200/07
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Methods of treating, managing or preventing exercise-induced asthma are disclosed. Specific methods encompass the administration of (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione alone or in combination with a second active agent. Pharmaceutical compositions and single unit dosage forms are also disclosed.