Heteroaryl substituted spirocyclic sulfamides for inhibition of gamma secretase
US7282513B2 · kind B2 · utility
4Cited by
3References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 2, 2006 |
| Grant date | Oct 16, 2007 |
| Priority date | — |
| Expiry date | Mar 2, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of formula I are disclosed:in which X is a 5-membered heteroaryl ring and R is as defined herein. The compounds are inhibitors of the processing of APP by gamma-secretase, and hence are useful in the treatment or prevention of Alzheimer's disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.