Medical uses of carbamate-substituted pyrazolo-pyridine derivatives

US7291622B2 · kind B2 · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Johannes-Peter Stasch · Wuppertal, DE
• Achim Feurer · Wilhelmsfeld, DE
• Stefan Weigand · Wuppertal, DE
• Elke Stahl · Bensberg, DE
• Dietmar Flubacher · Glückstadt, DE
• Cristina Alonso-Alija · Haan, DE
• Frank Wunder · Wuppertal, DE
• Dieter Lang · Velbert, DE
• Klaus Dembowsky · Boston, US
• Alexander Straub · Wuppertal, DE
• Elizabeth Perzborn · Wuppertal, DE

Key dates

• Filing date: Jul 29, 2005
• Grant date: Nov 6, 2007
• Expiry date: Jul 29, 2025

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P29/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to methods for treating sexual dysfunction, by administering a compound of the formulawherein R1 is H or a di-C1-6-alkylaminocarbonyl radical, and R2 is a radical of the formula —O—C(X)—NR3R4 wherein X is O or S. The compound may also be administered in combination with at least one organic nitrate or NO donor, or in combination with at least one compound which inhibits the breakdown of cyclic guanosine monophosphate (cGMP).