Methods of treating medical conditions using sulfonate-substituted pyrazolopyridine derivatives

US7317016B2 · kind B2 · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Johannes-Peter Stasch · Wuppertal, DE
• Achim Feurer · Wilhelmsfeld, DE
• Stefan Weigand · Wuppertal, DE
• Elke Stahl · Bensberg, DE
• Dietmar Flubacher · Glückstadt, DE
• Cristina Alonso-Alija · Haan, DE
• Frank Wunder · Wuppertal, DE
• Dieter Lang · Velbert, DE
• Klaus Dembowsky · Boston, US
• Alexander Straub · Wuppertal, DE
• Elisabeth Perzborn · Wuppertal, DE

Key dates

• Filing date: Jul 5, 2005
• Grant date: Jan 8, 2008
• Expiry date: Jul 5, 2025

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to methods of treatment of cardiovascular disorders, thromboembolic disorders, inflammation, and disorders of the central nervous system using pyrazol pyridine derivatives of formula (I)wherein R1 is a radical of the formula —O—SO2—R3 in which R3 is optionally substituted C1-6-alkyl, optionally substituted C3-8-cycloalkyl, or optionally substituted phenyl; R2 is H, optionally substituted C1-6-alkyl-CO— or optionally substituted C1-6-alkyl-SO2—; as well as salts, stereoisomers, tautomers, and hydrates thereof.