Cyclohexenyl phenyl carboxamides tocolytic oxytocin receptor antagonists
US7326700B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 10, 2002 |
| Grant date | Feb 5, 2008 |
| Priority date | — |
| Expiry date | Jan 7, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P15/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides tricyclic carboxamide compounds and methods and pharmaceutical compositions for their use in treatment, prevention, or suppression of disorders which may be remedied or alleviated by oxytocin antagonist activity, including prevention and/or suppression of preterm labor, suppression of labor at term prior to caesarean deliver, and for the treatment of dysmenorrhea. These compounds are also useful in enhancing fertility rates, enhancing survival rates and synchronizing estrus in farm animals; and may be useful in the prevention and treatment of disfunctions of the oxytocin system in the central nervous system including obsessive compulsive disorder (OCD) and neuropsychiatric disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.