Patent · US Expired

Substituted-1-phthalazinamines as vr-1 antagonists

US7329659B2 · kind B2 · utility

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8Claims
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Assignee

Inventors

Key dates

Filing dateApr 5, 2004
Grant dateFeb 12, 2008
Priority date
Expiry dateNov 3, 2024

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D471/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention provides a compound of formula (I): in which Ar and R1 are phenyl or a heteroaromatic group, R2 is generally hydrogen, R3 is hydrogen or alkyl and X, Y and Z are generally CH or N as VR-1 antagonists; or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising it; its use in therapy; use of it to manufacture medicaments to treat pain or inflammation; and methods of treating pain or inflammation

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.