Proteomic analysis
US7348437B2 · kind B2 · utility
4Cited by
3References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 1, 2005 |
| Grant date | Mar 25, 2008 |
| Priority date | — |
| Expiry date | Jun 1, 2025 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/96486
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Activity-based compositions for analyzing metalloproteases are disclosed, where the compositions include a chemical compound including a hydroxamate moiety and a benzophenone moiety. Methods for synthesizing these compounds are also disclosed, as well as methods of using them for determining the bioactivity of a compositions comprising active compounds toward a metalloproteases and for determining the potency of an inhibitor against a metalloprotease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.