Indol-3-yl-carbonyl-spiro-piperidine derivatives
US7351706B2 · kind B2 · utility
13Cited by
1References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 18, 2006 |
| Grant date | Apr 1, 2008 |
| Priority date | — |
| Expiry date | Dec 18, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/24
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to indol-3-yl-carbonyl-spiro-piperidine derivatives which act as V1a receptor antagonists and which are represented by Formula I:wherein the spiropiperidine-head group A and the residues R1, R2 and R3 are as defined herein. The invention further relates to pharmaceutical compositions containing such compounds, their use in the treatment of dysmenorrhea, hypertension, chronic heart failure, inappropriate secretion of vasopressin, liver cirrhosis, nephrotic syndrome, obsessive compulsive disorder, anxiety and depressive disorders, and to methods of preparation thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.