Nicotinamide benzofused-heterocyclyl derivatives useful as selective inhibitors of PDE4 isozymes
US7354941B2 · kind B2 · utility
10Cited by
1References
13Claims
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Key dates
| Filing date | Jan 30, 2001 |
| Grant date | Apr 8, 2008 |
| Priority date | — |
| Expiry date | Jan 16, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds useful as inhibitors of PDE4 in the treatment of diseases regulated by the activation and degranulation of eosinophils, especially asthma, chronic bronchitis, and chronic obstructive pulmonary disease, of Formula (1.0.0):wherein R5 and R6 are taken together to form a moiety of partial Formulas (1.1.1) through (1.1.5):or a pharmaceutically acceptable salt thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.