Processes for the preparation of paclitaxel
US7358378B2 · kind B2 · utility
1Cited by
16References
80Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 8, 2006 |
| Grant date | Apr 15, 2008 |
| Priority date | — |
| Expiry date | Jun 8, 2026 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides processes for the production of paclitaxel. Paclitaxel is produced by protecting the C(7) and the C(10) hydroxy groups of 10-DAB with a bridging silicon-based protecting group. The resulting 7,10-protected 10-DAB derivative is then derivatized and deprotected to form paclitaxel.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.