Patent · US Active

Anti-VEGF antibodies

US7365166B2 · kind B2 · utility

73Cited by

9References

7Claims

0Family size

Assignee

Genentech, Inc. · US

Inventors

Manuel Baca · Gaithersburg, US
James A. Wells · Burlingame, US
Leonard G. Presta · San Francisco, US
Henry B. Lowman · El Granada, US
Yvonne Chen · San Mateo, US

Key dates

Filing date	Sep 28, 2006
Grant date	Apr 29, 2008
Priority date	—
Expiry date	Oct 30, 2026

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/92
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Humanized and variant anti-VEGF antibodies and various uses therefor are disclosed. The anti-VEGF antibodies have strong binding affinities for VEGF; inhibit VEGF-induced proliferation of endothelial cells in vitro; and inhibit tumor growth in vivo.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.