In vivo incorporation of unnatural amino acids

US7368275B2 · kind B2 · utility

Assignees

• THE SCRIPPS RESEARCH INSTITUTE · US
• The Regents of the University of California · US

Inventors

• Peter G. Schultz · Village of La Jolla, US
• Lei Wang · Beijing, CN
• John Christopher Anderson · Kihei, US
• Jason W. Chin · Pidley, GB
• David R. Liu · Lexington, US
• Thomas J. Magliery · Columbus, US
• Eric Meggers · Philadelphia, US
• Ryan A. Mehl · San Diego, US
• Miro Pastrnak · San Diego, US
• Steven William Santoro · Cambridge, US
• Zhiwen Zhang · Austin, US

Key dates

• Filing date: Oct 18, 2005
• Grant date: May 6, 2008
• Expiry date: Oct 18, 2025

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12P21/02
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids.