Compositions comprising IMPDH inhibitors and uses thereof for treating HCV infection
US7371372B2 · kind B2 · utility
47Cited by
1References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 28, 2004 |
| Grant date | May 13, 2008 |
| Priority date | — |
| Expiry date | Jul 26, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to optimal compositions useful in treating HCV infections in humans. These compositions comprise alpha-interferon or pegylated alpha-interferon and an IMPDH inhibitor selected from VX-148 or VX-944, wherein the IMPDH inhibitor is present in an amount such that a ratio of Cavg/Cmin is between 1 to 10, wherein: The present invention also relates to methods of producing and using the optimal compositions to treat HCV infections in humans.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.