Dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions

US7371753B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Heinz Stadtmueller · Wien, AT
• Harald Engelhardt · Ebreichsdorf, AT
• Andreas Schoop · Overath, DE
• Martin Steegmaier · Wien, AT
• Matthias Hoffmann · Mittelbiberach, DE
• Matthias Grauert · Ingelheim am Rhein, DE

Key dates

• Filing date: Aug 25, 2005
• Grant date: May 13, 2008
• Expiry date: Sep 9, 2025

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed are new dihydropteridinones of general formula (I)wherein the groups R1 to R5, Ra to Rc, W, Q1 and Q2 have the meanings given in the claims and specification, the isomers thereof and the use thereof for preparing a pharmaceutical composition for the treatment of diseases characterised by excessive or abnormal cell proliferation.